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What are the
causes of diabetes? |
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You might ask yourself, why do I have diabetes? Have I done
something wrong? The answer is no. We know that the vast
majority of the tendency to diabetes is genetically
transmitted. If you are obese, your chances of developing
diabetes are much higher than if you are not obese but by the
same token we know that obesity has many genetic causes as
well. Therefore, rather than blame yourself for where you are
at, it is better to think of what can do to control your
diabetes and make your health better.
Type 2 diabetes is determined principally by a genetic factor,
that is, what is your heredity? If you have the gene(s) for
diabetes, you may or may not actually develop the disease
because to develop the disease usually something else has to
happen. That something else would be, for example, if you
allow yourself to become obese, if you do not do regular
exercise or just with increasing age, the chance of you
getting Type 2 diabetes becomes much greater.
It is the combination of having the genes and then having
something that makes it appear. Other factors that make it
appear are, the development of what is called “Insulin
Resistance”. Insulin is the hormone that allows blood sugar to
enter into the cells of the body and provide energy for the
cells. Blood sugar has to get into the cell and insulin is the
hormone that allows that to happen. In people who have genetic
Type 2 diabetes there is a resistance to the action of
insulin. In other words, prior to diabetes one molecule of
insulin would bring in one molecule of sugar. However, in
people who have early diabetes, they need two or three
molecules of insulin to get that same amount of sugar into the
bloodstream. As a result, early on in the development of
diabetes, they develop insulin resistance and can actually
have high levels of insulin but the insulin is not working
well, and they need more and more insulin, to get same amount
of energy (sugar) into the cells of the body.

You noticed that
before the blood sugar rises, it can stay very normal for a
long period of time. However, as you can see the top line of
the chart, the insulin resistance is getting worse and worse.
And as the insulin resistance gets worse, the body responds by
pouring out more and more insulin to try and do the same
amount of work. So insulin resistance increases in the top
line, your amount of insulin secretion increases as you see
the next line down, but the blood sugar still stays low.
However, at a certain point in life and it varies in each
individual, the pancreas starts to fail. It just cannot keep
producing the amount of insulin that you need to hold the
sugar down. When that happens you become overtly diabetic,
that means that the blood sugar now is not controllable any
longer. And as you see from this diagram, the insulin level
starts to fall and the blood sugar then starts to rise. Now we
have clear cut diabetes which was present probably for several
years before that but you were able to control it as you had
increased insulin secretion. Now you have developed Type 2
Diabetes and it is now very hard to control your blood sugars.
It can be made easier, however, by eating the right foods or
not demanding so much insulin when we eat a meal. The demand
for insulin depends upon how much and what type of
carbohydrates we ingest.
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